Multiple testing and error control in Gaussian graphical model selection

Mathias Drton, Michael D. Perlman

Research output: Contribution to journalReview articlepeer-review

86 Scopus citations

Abstract

Graphical models provide a framework for exploration of multivariate dependence patterns. The connection between graph and statistical model is made by identifying the vertices of the graph with the observed variables and translating the pattern of edges in the graph into a pattern of conditional independences that is imposed on the variables' joint distribution. Focusing on Gaussian models, we review classical graphical models. For these models the defining conditional independences are equivalent to vanishing of certain (partial) correlation coefficients associated with individual edges that are absent from the graph. Hence, Gaussian graphical model selection can be performed by multiple testing of hypotheses about vanishing (partial) correlation coefficients. We show and exemplify how this approach allows one to perform model selection while controlling error rates for incorrect edge inclusion.

Original languageEnglish
Pages (from-to)430-449
Number of pages20
JournalStatistical Science
Volume22
Issue number3
DOIs
StatePublished - Aug 2007
Externally publishedYes

Keywords

  • Acyclic directed graph
  • Bayesian network
  • Bidirected graph
  • Chain graph
  • Concentration graph
  • Covariance graph
  • DAG
  • Graphical model
  • Multiple testing
  • Undirected graph

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