Multiple sclerosis coinciding with Machado-Joseph disease

Jens E. Röhl; J. D. Lünemann; C. Zimmer; R. Zschenderlein; J. M. Valdueza

doi:10.1007/s10072-005-0447-0

Multiple sclerosis coinciding with Machado-Joseph disease

Jens E. Röhl
, J. D. Lünemann
, C. Zimmer
, R. Zschenderlein
, J. M. Valdueza

Charité – Universitätsmedizin Berlin
National Institutes of Health (NIH)
University of Leipzig
Bad Segeberger Kliniken

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI studies recently highlighted the extent of neuronal damage that occurs even in the early stages of the disease. We report the unusual case of a patient with Machado-Joseph disease (MJD; spinocerebellar ataxia (SCA) III) and discuss this coincidence in light current pathogenetic paradigms of CNS autoimmunity.

Original language	English
Pages (from-to)	135-136
Number of pages	2
Journal	Neurological Sciences
Volume	26
Issue number	2
DOIs	https://doi.org/10.1007/s10072-005-0447-0
State	Published - Jun 2005
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Chronic inflammatory CNS disease
Machado-Joseph disease (MJD)
Multiple sclerosis (MS)
Neurodegeneration

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10.1007/s10072-005-0447-0

Cite this

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title = "Multiple sclerosis coinciding with Machado-Joseph disease",

abstract = "Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI studies recently highlighted the extent of neuronal damage that occurs even in the early stages of the disease. We report the unusual case of a patient with Machado-Joseph disease (MJD; spinocerebellar ataxia (SCA) III) and discuss this coincidence in light current pathogenetic paradigms of CNS autoimmunity.",

keywords = "Chronic inflammatory CNS disease, Machado-Joseph disease (MJD), Multiple sclerosis (MS), Neurodegeneration",

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T1 - Multiple sclerosis coinciding with Machado-Joseph disease

AU - Röhl, Jens E.

AU - Lünemann, J. D.

AU - Zimmer, C.

AU - Zschenderlein, R.

AU - Valdueza, J. M.

PY - 2005/6

Y1 - 2005/6

N2 - Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI studies recently highlighted the extent of neuronal damage that occurs even in the early stages of the disease. We report the unusual case of a patient with Machado-Joseph disease (MJD; spinocerebellar ataxia (SCA) III) and discuss this coincidence in light current pathogenetic paradigms of CNS autoimmunity.

AB - Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI studies recently highlighted the extent of neuronal damage that occurs even in the early stages of the disease. We report the unusual case of a patient with Machado-Joseph disease (MJD; spinocerebellar ataxia (SCA) III) and discuss this coincidence in light current pathogenetic paradigms of CNS autoimmunity.

KW - Chronic inflammatory CNS disease

KW - Machado-Joseph disease (MJD)

KW - Multiple sclerosis (MS)

KW - Neurodegeneration

UR - https://www.scopus.com/pages/publications/22144498441

U2 - 10.1007/s10072-005-0447-0

DO - 10.1007/s10072-005-0447-0

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VL - 26

SP - 135

EP - 136

JO - Neurological Sciences

JF - Neurological Sciences

IS - 2

ER -

Multiple sclerosis coinciding with Machado-Joseph disease

Abstract

UN SDGs

Keywords

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