Multiple sclerosis coinciding with Machado-Joseph disease

Jens E. Röhl; J. D. Lünemann; C. Zimmer; R. Zschenderlein; J. M. Valdueza

doi:10.1007/s10072-005-0447-0

Multiple sclerosis coinciding with Machado-Joseph disease

Jens E. Röhl, J. D. Lünemann, C. Zimmer, R. Zschenderlein, J. M. Valdueza

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI studies recently highlighted the extent of neuronal damage that occurs even in the early stages of the disease. We report the unusual case of a patient with Machado-Joseph disease (MJD; spinocerebellar ataxia (SCA) III) and discuss this coincidence in light current pathogenetic paradigms of CNS autoimmunity.

Original language	English
Pages (from-to)	135-136
Number of pages	2
Journal	Neurological Sciences
Volume	26
Issue number	2
DOIs	https://doi.org/10.1007/s10072-005-0447-0
State	Published - Jun 2005
Externally published	Yes

Keywords

Chronic inflammatory CNS disease
Machado-Joseph disease (MJD)
Multiple sclerosis (MS)
Neurodegeneration

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10072-005-0447-0

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title = "Multiple sclerosis coinciding with Machado-Joseph disease",

abstract = "Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI studies recently highlighted the extent of neuronal damage that occurs even in the early stages of the disease. We report the unusual case of a patient with Machado-Joseph disease (MJD; spinocerebellar ataxia (SCA) III) and discuss this coincidence in light current pathogenetic paradigms of CNS autoimmunity.",

keywords = "Chronic inflammatory CNS disease, Machado-Joseph disease (MJD), Multiple sclerosis (MS), Neurodegeneration",

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AU - Röhl, Jens E.

AU - Lünemann, J. D.

AU - Zimmer, C.

AU - Zschenderlein, R.

AU - Valdueza, J. M.

PY - 2005/6

Y1 - 2005/6

N2 - Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI studies recently highlighted the extent of neuronal damage that occurs even in the early stages of the disease. We report the unusual case of a patient with Machado-Joseph disease (MJD; spinocerebellar ataxia (SCA) III) and discuss this coincidence in light current pathogenetic paradigms of CNS autoimmunity.

AB - Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI studies recently highlighted the extent of neuronal damage that occurs even in the early stages of the disease. We report the unusual case of a patient with Machado-Joseph disease (MJD; spinocerebellar ataxia (SCA) III) and discuss this coincidence in light current pathogenetic paradigms of CNS autoimmunity.

KW - Chronic inflammatory CNS disease

KW - Machado-Joseph disease (MJD)

KW - Multiple sclerosis (MS)

KW - Neurodegeneration

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JO - Neurological Sciences

JF - Neurological Sciences

IS - 2

ER -

Multiple sclerosis coinciding with Machado-Joseph disease

Abstract

Keywords

UN SDGs

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