@inproceedings{07a567bf762a4a259fe3467d665e4a62,
title = "Multiparametric neuroLab with integrated MEA & life support",
abstract = "The biology of neuronal cells is more complex than analyses of single molecular components can reveal. To understand the interactions of living neurons in their natural environment it is important to look at the functional mechanisms of cells. Stable culturing of neuronal networks over long periods of time requires strict control over biochemical parameters of the medium. Therefore the quantitative analysis of micro-environmental conditions and cell metabolic rates is essential in interpreting the changing patterns of electrophysiological activity. Changes in spontaneous spike production and oxygen consumption measured at the site of the network monolayer can provide rapid indications of metabolic disturbances. The developed biosensor supported neuro screening system NeuroLab helps to perform high content screening studies on living cells in a near invivo environment.",
keywords = "High content screening, MEA, Recording chamber, Sensor, pH",
author = "F. Ilchmann and J. Meyer and M. Schmidhuber and M. Zottmann and B. Becker and B. Wolf",
year = "2009",
doi = "10.1007/978-3-642-03887-7_21",
language = "English",
isbn = "9783642038860",
series = "IFMBE Proceedings",
publisher = "Springer Verlag",
number = "8",
pages = "77--79",
booktitle = "World Congress on Medical Physics and Biomedical Engineering",
edition = "8",
note = "World Congress on Medical Physics and Biomedical Engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors ; Conference date: 07-09-2009 Through 12-09-2009",
}