MRI lesions after invasive therapy of carotid artery stenosis: A risk-modeling analysis

H. Poppert, O. Wolf, W. Theiss, P. Heider, R. Hollweck, M. Roettinger, D. Sander

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Background: Diffusion-weighted imaging (DWI) abnormalities can frequently be detected after carotid endarterectomy (CEA) and carotid angioplasty with stent placement (CAS) of the carotid arteries. We looked for possible predictors for the development of DWI lesions during the intervention. Methods: We investigated 41 patients who underwent CAS without protection devices and 93 patients who underwent CEA. DWI studies were performed 1 day before and after the intervention. Results: Ischemic complications consisted of two strokes (2.2%) in the CEA group and one stroke (2.4%) in the CAS group. DWI lesions were detected in 28.0% of all patients after intervention. Using a multivariate regression analysis, diabetes mellitus (DM), hyperlipidemia, symptomatic stenosis, age and CAS were found to be significant predictors for the occurrence of DWI lesions. Conclusions: DWI is an objective and highly sensitive method for monitoring interventions of the carotid arteries. Our results point to an increased risk of patients with diabetes and hyperlipidemia to develop DWI lesions during invasive therapy of the ICA.

Original languageEnglish
Pages (from-to)563-567
Number of pages5
JournalNeurological Research
Volume28
Issue number5
DOIs
StatePublished - Jul 2006

Keywords

  • Angioplasty, ballon
  • Diabetes mellitus
  • Diffusion magnetic resonance
  • Endarterectomy, carotid imaging
  • Intracranial embolism

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