TY - GEN
T1 - Monitoring of tissue heating with medium intensity focused ultrasound via four dimensional optoacoustic tomography
AU - Oyaga Landa, Francisco Javier
AU - Ronda Penacoba, Silvia
AU - Deán-Ben, Xosé Luís
AU - Montero De Espinosa, Francisco
AU - Razansky, Daniel
N1 - Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.
PY - 2018
Y1 - 2018
N2 - Medium intensity focused ultrasound (MIFU) holds promise in important clinical applications. Generally, the aim in MIFU is to stimulate physiological mechanisms that reinforce healing responses, avoiding reaching temperatures that can cause permanent tissue damage. The outcome of interventions is then strongly affected by the temperature distribution in the treated region, and accurate monitoring represents a significant clinical need. In this work, we showcase the capacities of 4D optoacoustic imaging to monitor tissue heating during MIFU. The proposed method allows localizing the ultrasound focus, estimating the peak temperature and measuring the size of the heat-affected volume. Calibration experiments in a tissue-mimicking phantom demonstrate that the optoacoustically-estimated temperature accurately matches thermocouple readings. The good performance of the suggested approach in real tissues is further showcased in experiments with bovine muscle samples.
AB - Medium intensity focused ultrasound (MIFU) holds promise in important clinical applications. Generally, the aim in MIFU is to stimulate physiological mechanisms that reinforce healing responses, avoiding reaching temperatures that can cause permanent tissue damage. The outcome of interventions is then strongly affected by the temperature distribution in the treated region, and accurate monitoring represents a significant clinical need. In this work, we showcase the capacities of 4D optoacoustic imaging to monitor tissue heating during MIFU. The proposed method allows localizing the ultrasound focus, estimating the peak temperature and measuring the size of the heat-affected volume. Calibration experiments in a tissue-mimicking phantom demonstrate that the optoacoustically-estimated temperature accurately matches thermocouple readings. The good performance of the suggested approach in real tissues is further showcased in experiments with bovine muscle samples.
KW - Photoacoustic Imaging
KW - Temperature
KW - Thermal Imaging
KW - Ultrasound diagnostics
UR - https://www.scopus.com/pages/publications/85047358909
U2 - 10.1117/12.2288939
DO - 10.1117/12.2288939
M3 - Conference contribution
AN - SCOPUS:85047358909
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Photons Plus Ultrasound
A2 - Wang, Lihong V.
A2 - Oraevsky, Alexander A.
PB - SPIE
T2 - Photons Plus Ultrasound: Imaging and Sensing 2018
Y2 - 28 January 2018 through 1 February 2018
ER -