Molecular precision chemotherapy: Overcoming resistance to targeted therapies?

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Cytotoxic drugs may have specific effects on oncogenes and their downstream targets. Increase of cancer cell sensitivity due to repression of an oncogene downstream target can be specifically addressed by combined precision chemotherapy, increasing the therapeutic index of chemotherapy and overcoming resistance to highly selective targeted therapies.

Original languageEnglish
Pages (from-to)1064-1066
Number of pages3
JournalClinical Cancer Research
Volume20
Issue number5
DOIs
StatePublished - 2014

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