@inproceedings{9044e6ed42864a229a3590eb4ca3c3ea,
title = "Molecular determinants of the bittersweet janus head of steviol glycosides from stevia rebaudiana (Bert.) bertoni",
abstract = "To identify the structural requirements for the organoleptic properties of steviol glycosides from Stevia rebaudiana, we correlated in vivo data obtained from human psychophysical experiments with in vitro data from cell-based taste receptor assays. While sensory evaluation demonstrated the structural features causing the sweet and bitter taste of these sweeteners, screening experiments with the 25 human bitter taste receptors revealed hTAS2R4 and hTAS2R14 to be the general sensors for bitter taste elicited by steviol glycosides. These results help to navigate breeding of Stevia rebaudiana and improve postharvest downstream processing toward the production of preferentially sweet and least bitter tasting Stevia extracts.",
author = "C. Dawid and C. Well and A. Brockhoff and F. Stahler and W. Meyerhof and T. Hofmann",
note = "Publisher Copyright: {\textcopyright} 2015 American Chemical Society.",
year = "2015",
doi = "10.1021/bk-2015-1191.ch015",
language = "English",
series = "ACS Symposium Series",
publisher = "American Chemical Society",
pages = "197--207",
editor = "Brian Guthrie and Jonathan Beauchamp and Andrea Buettner and Lavine, {Barry K.}",
booktitle = "The Chemical Sensory Informatics of Food",
}