Molecular determinants of the bittersweet janus head of steviol glycosides from stevia rebaudiana (Bert.) bertoni

C. Dawid, C. Well, A. Brockhoff, F. Stahler, W. Meyerhof, T. Hofmann

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

To identify the structural requirements for the organoleptic properties of steviol glycosides from Stevia rebaudiana, we correlated in vivo data obtained from human psychophysical experiments with in vitro data from cell-based taste receptor assays. While sensory evaluation demonstrated the structural features causing the sweet and bitter taste of these sweeteners, screening experiments with the 25 human bitter taste receptors revealed hTAS2R4 and hTAS2R14 to be the general sensors for bitter taste elicited by steviol glycosides. These results help to navigate breeding of Stevia rebaudiana and improve postharvest downstream processing toward the production of preferentially sweet and least bitter tasting Stevia extracts.

Original languageEnglish
Title of host publicationThe Chemical Sensory Informatics of Food
Subtitle of host publicationMeasurement, Analysis, Integration
EditorsBrian Guthrie, Jonathan Beauchamp, Andrea Buettner, Barry K. Lavine
PublisherAmerican Chemical Society
Pages197-207
Number of pages11
ISBN (Electronic)9780841230699
DOIs
StatePublished - 2015

Publication series

NameACS Symposium Series
Volume1191
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

Fingerprint

Dive into the research topics of 'Molecular determinants of the bittersweet janus head of steviol glycosides from stevia rebaudiana (Bert.) bertoni'. Together they form a unique fingerprint.

Cite this