TY - JOUR
T1 - Modeling the shape of cylindrically focused transducers in three-dimensional optoacoustic tomography
AU - Queirós, Daniel
AU - Déan-Ben, Xosé Luís
AU - Buehler, Andreas
AU - Razansky, Daniel
AU - Rosenthal, Amir
AU - Ntziachristos, Vasilis
N1 - Funding Information:
Daniel Razansky acknowledges support from the ERC Starting Grant “Dynamit,” Grant agreement 260991. Vasilis Ntziachristos acknowledges support from the EU Framework Program 7, ERC Advanced Grant “MSOT,” Grant agreement 233161.
PY - 2013/7
Y1 - 2013/7
N2 - Cross sectional tomographic systems based on cylindrically focused transducers are widely used in optoacoustic (photoacoustic) imaging due to important advantages they provide such as high-cross sectional resolution, real-time imaging capacity, and high-throughput performance. Tomographic images in such systems are commonly obtained by means of two-dimensional (2-D) reconstruction procedures assuming point-like detectors, and volumetric (whole-body) imaging is performed by superimposing the cross sectional images for different positions along the scanning direction. Such reconstruction strategy generally leads to in-plane and out-of-plane artifacts as well as significant quantification errors. Herein, we introduce two equivalent full three-dimensional (3-D) models capable of accounting for the shape of cylindrically focused transducers. The performance of these models in 3-D reconstructions considering several scanning positions is analyzed in this work. Improvements of the results rendered with the introduced reconstruction procedure as compared with the 2-D-based approach are described and discussed for simulations and experiments with phantoms and biological tissues.
AB - Cross sectional tomographic systems based on cylindrically focused transducers are widely used in optoacoustic (photoacoustic) imaging due to important advantages they provide such as high-cross sectional resolution, real-time imaging capacity, and high-throughput performance. Tomographic images in such systems are commonly obtained by means of two-dimensional (2-D) reconstruction procedures assuming point-like detectors, and volumetric (whole-body) imaging is performed by superimposing the cross sectional images for different positions along the scanning direction. Such reconstruction strategy generally leads to in-plane and out-of-plane artifacts as well as significant quantification errors. Herein, we introduce two equivalent full three-dimensional (3-D) models capable of accounting for the shape of cylindrically focused transducers. The performance of these models in 3-D reconstructions considering several scanning positions is analyzed in this work. Improvements of the results rendered with the introduced reconstruction procedure as compared with the 2-D-based approach are described and discussed for simulations and experiments with phantoms and biological tissues.
KW - focused transducer
KW - image reconstruction
KW - optoacoustic tomography
KW - photoacoustic tomography
UR - http://www.scopus.com/inward/record.url?scp=84888229332&partnerID=8YFLogxK
U2 - 10.1117/1.JBO.18.7.076014
DO - 10.1117/1.JBO.18.7.076014
M3 - Article
C2 - 23864012
AN - SCOPUS:84888229332
SN - 1083-3668
VL - 18
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
IS - 7
M1 - 076014
ER -