MIPS PlantsDB: A database framework for comparative plant genome research

Thomas Nussbaumer, Mihaela M. Martis, Stephan K. Roessner, Matthias Pfeifer, Kai C. Bader, Sapna Sharma, Heidrun Gundlach, Manuel Spannagl

Research output: Contribution to journalArticlepeer-review

142 Scopus citations

Abstract

The rapidly increasing amount of plant genome (sequence) data enables powerful comparative analyses and integrative approaches and also requires structured and comprehensive information resources. Databases are needed for both model and crop plant organisms and both intuitive search/browse views and comparative genomics tools should communicate the data to researchers and help them interpret it. MIPS PlantsDB (http://mips.helmholtz-muenchen.de/plant/ genomes.jsp) was initially described in NAR in 2007 [Spannagl, M., Noubibou, O., Haase, D., Yang, L., Gundlach, H., Hindemitt, T., Klee, K., Haberer, G., Schoof, H. and Mayer, K.F. (2007) MIPSPlantsDB-plant database resource for integrative and comparative plant genome research. Nucleic Acids Res., 35, D834-D840] and was set up from the start to provide data and information resources for individual plant species as well as a framework for integrative and comparative plant genome research. PlantsDB comprises database instances for tomato, Medicago, Arabidopsis, Brachypodium, Sorghum, maize, rice, barley and wheat. Building up on that, state-of-the-art comparative genomics tools such as CrowsNest are integrated to visualize and investigate syntenic relationships between monocot genomes. Results from novel genome analysis strategies targeting the complex and repetitive genomes of triticeae species (wheat and barley) are provided and cross-linked with model species. The MIPS Repeat Element Database (mips-REdat) and Catalog (mips-REcat) as well as tight connections to other databases, e.g. via web services, are further important components of PlantsDB.

Original languageEnglish
Pages (from-to)D1144-D1151
JournalNucleic Acids Research
Volume41
Issue numberD1
DOIs
StatePublished - 1 Jan 2013
Externally publishedYes

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