Mild cognitive impairment: making headway by stepping backwards.

Hans Förstl, Nicola Lautenschlager, Horst Bickel

Research output: Contribution to journalReview articlepeer-review


Mild cognitive impairment (MCI) is a prevalent medical problem and the concept and term have become a catch-phrase for research and clinical practice. However, little is known about the most effective tools for a clinical diagnosis of MCI, its potential significance for individual patients and the best possible intervention--at least as long as MCI is considered as a diagnostic entity. We propose a simplified diagnostic and interventional algorithm for the detection and management of patients with MCI. We argue that MCI is so important, because it represents the closest call for an identification of treatable diseases or risk factors before the final manifestation of irreversible brain changes. Stepping backward by focussing on underlying disease processes and attempting causal interventions must be preferred to a mere symptomatic treatment of MCI as a preclinical form of Alzheimer's disease.

Original languageEnglish
Pages (from-to)370-380
Number of pages11
JournalSeishin shinkeigaku zasshi = Psychiatria et neurologia Japonica
Issue number4
StatePublished - 2003
Externally publishedYes


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