"metabolomics" in der Diabetesforschung

K. Wörmann; M. Lucio; S. Forcisi; S. S. Heinzmann; E. Kenar; H. Franken; L. Rosenbaum; P. Schmitt-Kopplin; O. Kohlbacher; A. Zell; H. U. Häring; R. Lehmann

doi:10.1007/s11428-011-0778-9

"metabolomics" in der Diabetesforschung

Translated title of the contribution: Metabolomics in diabetes research

K. Wörmann, M. Lucio, S. Forcisi, S. S. Heinzmann, E. Kenar, H. Franken, L. Rosenbaum, P. Schmitt-Kopplin, O. Kohlbacher, A. Zell, H. U. Häring, R. Lehmann

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Recently a new promising strategy has been introduced to the well-established approaches in diabetes research. Biomedical metabolomic analyses comprise the examination of metabolite patterns in different body fluids, tissues or samples from cell culture experiments with the objective to maximize the simultaneous detection of intermediate and end products of metabolism. Metabolomic analysis in diabetes research could provide new insights in the pathogenetic scenario of prediabetes, diabetes and its late complications as well as the discovery of novel diagnostic biomarkers. This review provides an overview of metabolomic analyses and a summary of current research results in metabolomics in diabetes research.

Translated title of the contribution	Metabolomics in diabetes research
Original language	German
Pages (from-to)	42-48
Number of pages	7
Journal	Diabetologe
Volume	8
Issue number	1
DOIs	https://doi.org/10.1007/s11428-011-0778-9
State	Published - Jan 2012
Externally published	Yes

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keywords = "Acylcarnitine, Biomarkers, Diabetes, Insulin resistance, Prediabetes",

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AU - Wörmann, K.

AU - Lucio, M.

AU - Forcisi, S.

AU - Heinzmann, S. S.

AU - Kenar, E.

AU - Franken, H.

AU - Rosenbaum, L.

AU - Schmitt-Kopplin, P.

AU - Kohlbacher, O.

AU - Zell, A.

AU - Häring, H. U.

AU - Lehmann, R.

PY - 2012/1

Y1 - 2012/1

N2 - Recently a new promising strategy has been introduced to the well-established approaches in diabetes research. Biomedical metabolomic analyses comprise the examination of metabolite patterns in different body fluids, tissues or samples from cell culture experiments with the objective to maximize the simultaneous detection of intermediate and end products of metabolism. Metabolomic analysis in diabetes research could provide new insights in the pathogenetic scenario of prediabetes, diabetes and its late complications as well as the discovery of novel diagnostic biomarkers. This review provides an overview of metabolomic analyses and a summary of current research results in metabolomics in diabetes research.

AB - Recently a new promising strategy has been introduced to the well-established approaches in diabetes research. Biomedical metabolomic analyses comprise the examination of metabolite patterns in different body fluids, tissues or samples from cell culture experiments with the objective to maximize the simultaneous detection of intermediate and end products of metabolism. Metabolomic analysis in diabetes research could provide new insights in the pathogenetic scenario of prediabetes, diabetes and its late complications as well as the discovery of novel diagnostic biomarkers. This review provides an overview of metabolomic analyses and a summary of current research results in metabolomics in diabetes research.

KW - Acylcarnitine

KW - Biomarkers

KW - Diabetes

KW - Insulin resistance

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"metabolomics" in der Diabetesforschung

Abstract

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