Mediating specific cell adhesion to low-adhesive diblock copolymers by instant modification with RGD-peptides

  • M. Hacker
  • , E. Lieb
  • , J. Tessmar
  • , J. Fiedler
  • , C. Dahmen
  • , U. Hersel
  • , H. Kessler
  • , M. B. Schulz
  • , A. Göpferich

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The modification of low-adhesive diblock copolymers with RGD-peptides to mediate specific cell adhesion was described. Human osteoblast known to express the corresponding integrins were used to determine cell-polymer interactions. The low-adhesive surfaces were modified by covalently attaching cyclic RGD-peptides in an instant procedure. It was observed that all RGD-modified polymer films showed increased cell adhesion. Cells were widely spread on the RGD-peptide modified films, indicating strong cell-surface interactions.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages1101
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
Country/TerritoryAustralia
CitySydney
Period17/05/0421/05/04

Fingerprint

Dive into the research topics of 'Mediating specific cell adhesion to low-adhesive diblock copolymers by instant modification with RGD-peptides'. Together they form a unique fingerprint.

Cite this