TY - JOUR
T1 - Masked left ventricular restriction in elderly patients with atrial septal defects
T2 - A contraindication for closure?
AU - Ewert, Peter
AU - Berger, Felix
AU - Nagdyman, Nicole
AU - Kretschmar, Oliver
AU - Dittrich, Sven
AU - Abdul-Khaliq, Hashim
AU - Lange, Peter E.
PY - 2001
Y1 - 2001
N2 - The impact of an atrial septal defect in the elderly with reduced diastolic elasticity of the left ventricle is unclear. We studied the hemodynamic changes during balloon occlusion of atrial septal defects in patients over 60 years of age. In 18 patients (61-78 years old; median, 70), the left atrial pressure and the mitral valve inflow was measured during complete balloon occlusion of the defect and after deflation of the balloon. In seven patients, the left atrial pressure and the E/A ratio of the mitral valve inflow increased markedly (P = 0.02). Mean atrial pressures reached values of 27 mm Hg and the v-wave peak values of 55 mm Hg. Two patients received a transcatheter device closure and developed congestive heart failure. In the elderly, an atrial septal defect can have a decompressive impact on the left ventricle. Therefore, caution appears to be warranted if atrial septal closure is planned.
AB - The impact of an atrial septal defect in the elderly with reduced diastolic elasticity of the left ventricle is unclear. We studied the hemodynamic changes during balloon occlusion of atrial septal defects in patients over 60 years of age. In 18 patients (61-78 years old; median, 70), the left atrial pressure and the mitral valve inflow was measured during complete balloon occlusion of the defect and after deflation of the balloon. In seven patients, the left atrial pressure and the E/A ratio of the mitral valve inflow increased markedly (P = 0.02). Mean atrial pressures reached values of 27 mm Hg and the v-wave peak values of 55 mm Hg. Two patients received a transcatheter device closure and developed congestive heart failure. In the elderly, an atrial septal defect can have a decompressive impact on the left ventricle. Therefore, caution appears to be warranted if atrial septal closure is planned.
KW - Atrial septal defect
KW - Balloon sizing
KW - Left ventricular diastolic function
KW - Restrictive left ventricular filling
KW - Transcatheter closure
UR - http://www.scopus.com/inward/record.url?scp=0035141339&partnerID=8YFLogxK
U2 - 10.1002/1522-726X(200102)52:2<177::AID-CCD1043>3.0.CO;2-G
DO - 10.1002/1522-726X(200102)52:2<177::AID-CCD1043>3.0.CO;2-G
M3 - Article
C2 - 11170324
AN - SCOPUS:0035141339
SN - 1522-1946
VL - 52
SP - 177
EP - 180
JO - Catheterization and Cardiovascular Interventions
JF - Catheterization and Cardiovascular Interventions
IS - 2
ER -