Management of Locally Advanced Gastroesophageal Cancer: Still a Multidisciplinary Global Challenge?

Salah Eddin Al-Batran, Sylvie Lorenzen

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

The outcome of patients with locally advanced, resectable gastric cancer, or adenocarcinoma of the gastroesophageal junction is poor. In clinical trials, multimodality therapy, such as perioperative chemotherapy, preoperative or postoperative chemoradiation, or adjuvant chemotherapy led to significant increments in survival. Therefore, experts agree that patients with stage II or III disease should be offered a multidisciplinary treatment approach. However, patients are treated somewhat differently in the different regions of the world and survival rates remain far from being satisfactory. Efforts to further improve outcome are highly warranted.

Original languageEnglish
Pages (from-to)441-452
Number of pages12
JournalHematology/Oncology Clinics of North America
Volume31
Issue number3
DOIs
StatePublished - Jun 2017
Externally publishedYes

Keywords

  • Chemotherapy
  • Gastroesophageal cancer
  • Locally advanced
  • Perioperative

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