Low temperature domino reactions. A ready access to trifluoromethyl substituted butenolides and their thioanalogues

Klaus Burger; Annett Fuchs; Lothar Hennig; Brigitte Helmreich

doi:10.1016/S0040-4039(01)00013-2

Low temperature domino reactions. A ready access to trifluoromethyl substituted butenolides and their thioanalogues

Klaus Burger
, Annett Fuchs
, Lothar Hennig
, Brigitte Helmreich

University of Leipzig

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Domino reactions are described, including nucleophilic substitution, Claisen rearrangement and Cope rearrangement, which provide ready access to trifluoromethyl substituted butenolides and their thioanalogues, starting from 2-fluoro-3-trifluoromethyl furans and thiophenes, respectively.

Original language	English
Pages (from-to)	1657-1659
Number of pages	3
Journal	Tetrahedron Letters
Volume	42
Issue number	9
DOIs	https://doi.org/10.1016/S0040-4039(01)00013-2
State	Published - 26 Feb 2001
Externally published	Yes

Keywords

3-trifluoromethyl-2(3H)furanones
3-trifluoromethyl-2(3H)thiophenones
3-trifluoromethyl-2(5H)-thiophenones
3-trifluoromethyl-2(5H)furanones
Domino reactions
Membrane transport systems

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10.1016/S0040-4039(01)00013-2

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title = "Low temperature domino reactions. A ready access to trifluoromethyl substituted butenolides and their thioanalogues",

abstract = "Domino reactions are described, including nucleophilic substitution, Claisen rearrangement and Cope rearrangement, which provide ready access to trifluoromethyl substituted butenolides and their thioanalogues, starting from 2-fluoro-3-trifluoromethyl furans and thiophenes, respectively.",

keywords = "3-trifluoromethyl-2(3H)furanones, 3-trifluoromethyl-2(3H)thiophenones, 3-trifluoromethyl-2(5H)-thiophenones, 3-trifluoromethyl-2(5H)furanones, Domino reactions, Membrane transport systems",

author = "Klaus Burger and Annett Fuchs and Lothar Hennig and Brigitte Helmreich",

note = "Funding Information: We thank the Deutsche Forschungsgemeinschaft (Bu 277/20-1) and the Fonds der Chemischen Industrie for financial support. ",

year = "2001",

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doi = "10.1016/S0040-4039(01)00013-2",

language = "English",

volume = "42",

pages = "1657--1659",

journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Low temperature domino reactions. A ready access to trifluoromethyl substituted butenolides and their thioanalogues

AU - Burger, Klaus

AU - Fuchs, Annett

AU - Hennig, Lothar

AU - Helmreich, Brigitte

N1 - Funding Information: We thank the Deutsche Forschungsgemeinschaft (Bu 277/20-1) and the Fonds der Chemischen Industrie for financial support.

PY - 2001/2/26

Y1 - 2001/2/26

N2 - Domino reactions are described, including nucleophilic substitution, Claisen rearrangement and Cope rearrangement, which provide ready access to trifluoromethyl substituted butenolides and their thioanalogues, starting from 2-fluoro-3-trifluoromethyl furans and thiophenes, respectively.

AB - Domino reactions are described, including nucleophilic substitution, Claisen rearrangement and Cope rearrangement, which provide ready access to trifluoromethyl substituted butenolides and their thioanalogues, starting from 2-fluoro-3-trifluoromethyl furans and thiophenes, respectively.

KW - 3-trifluoromethyl-2(3H)furanones

KW - 3-trifluoromethyl-2(3H)thiophenones

KW - 3-trifluoromethyl-2(5H)-thiophenones

KW - 3-trifluoromethyl-2(5H)furanones

KW - Domino reactions

KW - Membrane transport systems

UR - https://www.scopus.com/pages/publications/0035951918

U2 - 10.1016/S0040-4039(01)00013-2

DO - 10.1016/S0040-4039(01)00013-2

M3 - Article

AN - SCOPUS:0035951918

SN - 0040-4039

VL - 42

SP - 1657

EP - 1659

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 9

ER -

Low temperature domino reactions. A ready access to trifluoromethyl substituted butenolides and their thioanalogues

Abstract

Keywords

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