Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency

Anika Reifschneider, Sophie Robinson, Bettina van Lengerich, Johannes Gnörich, Todd Logan, Steffanie Heindl, Miriam A. Vogt, Endy Weidinger, Lina Riedl, Karin Wind, Artem Zatcepin, Ida Pesämaa, Sophie Haberl, Brigitte Nuscher, Gernot Kleinberger, Julien Klimmt, Julia K. Götzl, Arthur Liesz, Katharina Bürger, Matthias BrendelJohannes Levin, Janine Diehl-Schmid, Jung Suh, Gilbert Di Paolo, Joseph W. Lewcock, Kathryn M. Monroe, Dominik Paquet, Anja Capell, Christian Haass

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Medicine and Dentistry

Neuroscience

Pharmacology, Toxicology and Pharmaceutical Science