Longitudinal cortical registration for developing neonates

Hui Xue, Latha Srinivasan, Shuzhou Jiang, Mary Rutherford, A. David Edwards, Daniel Rueckert, Joseph V. Hajnal

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

11 Scopus citations

Abstract

Understanding the rapid evolution of cerebral cortical surfaces in developing neonates is essential in order to understand normal human brain development and to study anatomical abnormalities in preterm infants. Several methods to model and align cortical surfaces for cross-sectional studies have been developed. However, the registration of cortical surfaces extracted from neonates across different gestational ages for longitudinal studies remains difficult because of significant cerebral growth. In this paper, we present an automatic cortex registration algorithm, based on surface relaxation followed by non-rigid surface registration. This technique aims to establish the longitudinal spatial correspondence of cerebral cortices for the developing brain in neonates. The algorithm has been tested on 5 neonates. Each infant has been scanned at three different time points. Quantitative results are obtained by propagating sulci across multiple gestational ages and computing the overlap ratios with manually established ground-truth.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings
PublisherSpringer Verlag
Pages127-135
Number of pages9
EditionPART 2
ISBN (Print)9783540757580
DOIs
StatePublished - 2007
Externally publishedYes
Event10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007 - Brisbane, Australia
Duration: 29 Oct 20072 Nov 2007

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume4792 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007
Country/TerritoryAustralia
CityBrisbane
Period29/10/072/11/07

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