Local motion correction and influence of attenuation correction in combined positron emission and X-ray computed tomography

R. A. Bundschuh, A. Martínez-Möller, M. Essler, G. Delso, S. G. Nekolla, M. Schwaiger, S. I. Ziegler

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Movement in the area of the lung and the upper abdomen leads to motion blurring in PET images and to misalignment between PET data and CT data used for attenuation correction. This leads to errors in the quantification of the PET data, especially for lesion size and activity uptake. To minimize motion artifacts in the PET images, a local motion correction based on list-mode data was performed. The remaining problem of possible misalignment between PET and the CT based attenuation map, was studied using Monte Carlo simulations. An emission data driven correction of the attenuation map was used to reconstruct the PET data. This was performed for nine patients with solitary lung lesions. Using only the local motion correction a change of measured lesion volume of up to 27 % (mean 14.5 %) and of measured tracer uptake of up to 13 % (mean 4.7 %) was found. If additionally the data driven corrected attenuation map was applied, the changes were up to 54 % (mean 19.7 %) for the lesion volume and up to 36 % (mean 16.7 %) for the tracer uptake. This shows that local motion correction in combination with the data driven attenuation map improves the PET/CT data quantification of lesions in areas with movement.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering
Subtitle of host publicationDiagnostic Imaging
PublisherSpringer Verlag
Pages636-638
Number of pages3
Edition2
ISBN (Print)9783642038785
DOIs
StatePublished - 2009
Externally publishedYes
EventWorld Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging - Munich, Germany
Duration: 7 Sep 200912 Sep 2009

Publication series

NameIFMBE Proceedings
Number2
Volume25
ISSN (Print)1680-0737

Conference

ConferenceWorld Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging
Country/TerritoryGermany
CityMunich
Period7/09/0912/09/09

Keywords

  • Motion correction
  • PET/CT
  • Respiratory motion

Fingerprint

Dive into the research topics of 'Local motion correction and influence of attenuation correction in combined positron emission and X-ray computed tomography'. Together they form a unique fingerprint.

Cite this