TY - JOUR
T1 - Lipomatous metaplasia after severe and chronic cutaneous inflammation
AU - Eyerich, Kilian
AU - Traidl-Hoffmann, Claudia
AU - Albert, Annette
AU - Kerzl, Regina
AU - Rombold, Stephanie
AU - Darsow, Ulf
AU - Eberlein, Bernadette
AU - Jakob, Thilo
AU - Ring, Johannes
AU - Hein, Rüdiger
PY - 2008/6
Y1 - 2008/6
N2 - A 69-year-old woman with a history of acute generalized exanthematic pustulosis (AGEP) caused by metamizole is described. Furthermore, she had suffered from an untreated psoriasis since the age of 20. After an adequate therapy of both psoriasis and AGEP, yellow-brownish, static, coalescing, lucent nodules on the thighs and upper arms became apparent. Histology of skin biopsies revealed a prominent band of mature adipocytes in the dermis. We diagnosed a lipomatous metaplasia of the dermis and hypothesize that this metaplasia occurred as a consequence of the severe and chronic inflammation of the skin.
AB - A 69-year-old woman with a history of acute generalized exanthematic pustulosis (AGEP) caused by metamizole is described. Furthermore, she had suffered from an untreated psoriasis since the age of 20. After an adequate therapy of both psoriasis and AGEP, yellow-brownish, static, coalescing, lucent nodules on the thighs and upper arms became apparent. Histology of skin biopsies revealed a prominent band of mature adipocytes in the dermis. We diagnosed a lipomatous metaplasia of the dermis and hypothesize that this metaplasia occurred as a consequence of the severe and chronic inflammation of the skin.
KW - Cutaneous inflammation
KW - Dermis
KW - Metaplasia, lipomatous
UR - http://www.scopus.com/inward/record.url?scp=46049092578&partnerID=8YFLogxK
U2 - 10.1159/000123234
DO - 10.1159/000123234
M3 - Article
C2 - 18382104
AN - SCOPUS:46049092578
SN - 1018-8665
VL - 217
SP - 52
EP - 55
JO - Dermatology
JF - Dermatology
IS - 1
ER -