LINE(1)s of evidence in HBV-driven liver cancer

Mathias Heikenwalder, Ulrike Protzer

Research output: Contribution to journalShort surveypeer-review

13 Scopus citations


Hepatitis B virus (HBV) integration in hepatocellular carcinoma (HCC) is a poorly understood event. In a recent Cancer Cell paper, Lau et al. (2014) describe a HBV-human fusion transcript (HBx-LINE1) that functions as a lncRNA, influences the epithelial-mesenchymal transition, and correlates with reduced patient survival and tumor formation in mice.

Original languageEnglish
Pages (from-to)249-250
Number of pages2
JournalCell Host and Microbe
Issue number3
StatePublished - 12 Mar 2014


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