TY - JOUR
T1 - Life Is Degrading-Thanks to Some Zomes
AU - von Arnim, Albrecht G.
AU - Schwechheimer, Claus
N1 - Funding Information:
Zomes IV was financially supported by Yale University; the U.S. Department of Agriculture; Abcam; BIOMOL International; Genentech, Inc.; Eli Lilly; the Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology; and Danyel Biotech. Space constraints compelled us to omit many noteworthy advances and otherwise appropriate literature citations. Work in the authors' laboratories is supported by the Deutsche Forschungsgemeinschaft (CS) and by the U.S. Department of Energy, the National Science Foundation, and the U.S. Israel BARD Fund (AGvA).
PY - 2006/9/1
Y1 - 2006/9/1
N2 - Three structurally related protein complexes, the COP9 signalosome, the proteasome lid, and the eukaryotic translation initiation factor 3, are revealing new insights into developmental processes and into cell cycle control in healthy cells and cells exposed to genotoxic stress. Newly discovered cullin-RING E3 ubiquitin ligases assembled on the CUL4 platform may provide links between DNA replication, chromatin, and proteolysis.
AB - Three structurally related protein complexes, the COP9 signalosome, the proteasome lid, and the eukaryotic translation initiation factor 3, are revealing new insights into developmental processes and into cell cycle control in healthy cells and cells exposed to genotoxic stress. Newly discovered cullin-RING E3 ubiquitin ligases assembled on the CUL4 platform may provide links between DNA replication, chromatin, and proteolysis.
UR - http://www.scopus.com/inward/record.url?scp=33747881744&partnerID=8YFLogxK
U2 - 10.1016/j.molcel.2006.08.012
DO - 10.1016/j.molcel.2006.08.012
M3 - Article
C2 - 16977699
AN - SCOPUS:33747881744
SN - 1097-2765
VL - 23
SP - 621
EP - 629
JO - Molecular Cell
JF - Molecular Cell
IS - 5
ER -