TY - GEN
T1 - Learning cellular texture features in microscopic cancer cell images for automated cell-detection
AU - Kazmar, Tomáš
AU - Šmíd, Matěj
AU - Fuchs, Margit
AU - Luber, Birgit
AU - Mattes, Julian
PY - 2010
Y1 - 2010
N2 - In this paper we present a new approach for automated cell detection in single frames of 2D microscopic phase contrast images of cancer cells which is based on learning cellular texture features. The main challenge addressed in this paper is to deal with clusters of cells where each cell has a rather complex appearance composed of sub-regions with different texture features. Our approach works on two different levels of abstraction. First, we apply statistical learning to learn 6 different types of different local cellular texture features, classify each pixel according to them and we obtain an image partition composed of 6 different pixel categories. Based on this partitioned image we decide in a second step if pre-selected seeds belong to the same cell or not. Experimental results show the high accuracy of the proposed method and especially average precision above 95%.
AB - In this paper we present a new approach for automated cell detection in single frames of 2D microscopic phase contrast images of cancer cells which is based on learning cellular texture features. The main challenge addressed in this paper is to deal with clusters of cells where each cell has a rather complex appearance composed of sub-regions with different texture features. Our approach works on two different levels of abstraction. First, we apply statistical learning to learn 6 different types of different local cellular texture features, classify each pixel according to them and we obtain an image partition composed of 6 different pixel categories. Based on this partitioned image we decide in a second step if pre-selected seeds belong to the same cell or not. Experimental results show the high accuracy of the proposed method and especially average precision above 95%.
UR - http://www.scopus.com/inward/record.url?scp=78650837136&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2010.5626299
DO - 10.1109/IEMBS.2010.5626299
M3 - Conference contribution
C2 - 21095879
AN - SCOPUS:78650837136
SN - 9781424441235
T3 - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
SP - 49
EP - 52
BT - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
T2 - 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Y2 - 31 August 2010 through 4 September 2010
ER -
