Large-scale production of mouse phenotypes: the search for animal models for inherited diseases in humans.

M. Hrabé de Angelis, M. Strivens

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

This paper is aimed principally at bioinformaticians and biologists as an introduction to recent advances in mouse mutagenesis, concentrating on genome-wide screens utilising the powerful mutagen N-ethyl-N-nitroso-urea (ENU). It contains a brief background to the underlying genetics as well as details of the practical aspects of organisation and data capture for such projects.

Original languageEnglish
Pages (from-to)170-180
Number of pages11
JournalBriefings in Bioinformatics
Volume2
Issue number2
DOIs
StatePublished - May 2001
Externally publishedYes

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