TY - GEN
T1 - Lack of recovery of baroreflex function in hypertensive patients after heart surgery
AU - Bauernschmitt, Robert
AU - Wessel, N.
AU - Malberg, H.
AU - Brockmann, G.
AU - Lange, R.
PY - 2006
Y1 - 2006
N2 - Baroreflex sensitivity (BRS) and heart rate variability (HRV) have significant influence on the patients' prognosis after cardiovascular events. The following study was performed to assess differences in the response of the autonomic regulation in hypertensive and normotensive patients undergoing cardiac surgery with heart-lung machine. 166 consecutive patients were enrolled in a prospective study; 102 of them were hypertensive according to the criteria of the WHO. Cardiovascular signals were recorded the day before, 24h after surgery and one week after surgery. SDNN steeply declined in Hypertensives 24h after the operation (46.5 vs. 24.5ms, p<10-7 ), the decline in Normotensives was less pronounced (52 vs. 30.8ms, p<0.01).The mean number of bradycardic fluctuations of BRS decreased in both groups at 24h, then there was recovery in Normotensives after one week, but not in Hypertensives. While the response to surgery is similar in normotensive and hypertensive patients, there obviously is a decreased ability to recover in Hypertensives.
AB - Baroreflex sensitivity (BRS) and heart rate variability (HRV) have significant influence on the patients' prognosis after cardiovascular events. The following study was performed to assess differences in the response of the autonomic regulation in hypertensive and normotensive patients undergoing cardiac surgery with heart-lung machine. 166 consecutive patients were enrolled in a prospective study; 102 of them were hypertensive according to the criteria of the WHO. Cardiovascular signals were recorded the day before, 24h after surgery and one week after surgery. SDNN steeply declined in Hypertensives 24h after the operation (46.5 vs. 24.5ms, p<10-7 ), the decline in Normotensives was less pronounced (52 vs. 30.8ms, p<0.01).The mean number of bradycardic fluctuations of BRS decreased in both groups at 24h, then there was recovery in Normotensives after one week, but not in Hypertensives. While the response to surgery is similar in normotensive and hypertensive patients, there obviously is a decreased ability to recover in Hypertensives.
UR - http://www.scopus.com/inward/record.url?scp=50149088585&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:50149088585
SN - 1424425328
SN - 9781424425327
T3 - Computers in Cardiology
SP - 645
EP - 648
BT - 2006 Computers in Cardiology, CIC
T2 - 2006 Computers in Cardiology, CIC
Y2 - 17 September 2006 through 20 September 2006
ER -