Kraftspektroskopie - Dynamik und Manipulation einzelner Moleküle: Einzelmolekülanalyse

Translated title of the contribution: Single molecule analysis: Force spectroscopy - Dynamics and manipulation of single molecules

Gabriel Žoldák, Matthias Rief

Research output: Contribution to journalArticlepeer-review

Abstract

Over the last decade, the development of single molecule methods has allowed us to interface individual biomolecules, to subject them to mechanical load and to measure their conformational response. In this article, we introduce the new possibilities of force spectroscopy by AFM (atomic force microscope) and optical tweezers for the study of proteins. Applications of force spectroscopy for protein folding as well as force-dependent ligand binding in cell adhesion are discussed.

Translated title of the contributionSingle molecule analysis: Force spectroscopy - Dynamics and manipulation of single molecules
Original languageGerman
Pages (from-to)33-35
Number of pages3
JournalBioSpektrum
Volume20
Issue number1
DOIs
StatePublished - Feb 2014

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