KORRELATION MORPHOLOGISCHER KRITERIEN MIT DER WACHSTUMSGESCHWINDIGKEIT BEIM MAMMAKARZINOM

Translated title of the contribution: Correlation of morphological criteria with the rate of growth in carcinoma of the breast

W. Kuhn, D. von Fournier, G. Leppien, H. H. Rummel, A. Müller, G. Dick

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Prognosis of carcinoma of the breast depends on a number of factors. Besides tumor staging, these parameters include the number of axillary lymph nodes with metastatic growths, the status of the hormonal receptors, and the histological type of the tumor, especially the tumour grading and the rate of growth correlated therewith. The first few of these criteria are relatively easy to determine. The tumour duplication time has so far been determined only by means of serial mammographies. Only few studies have been conducted on the correlation of the morphological parameters connected with the dynamics of growth of carcinomas of the breast. In a group of 61 patients with carcinoma of the breast and known tumor duplication time determined by serial mammography, it is shown that broadening of the conventional tumour grading by means of additional histopathological malignancy criteria (frequency of mitosis, incidence of nuclear hyperchromasias, formation of tubules and nuclear irregularities) correlates with the growth dynamics of the tumours. This makes it seem possible to draw prospective conclusions on the growth performance of carcinomas of the breast even without restoring to serial mammographies.

Translated title of the contributionCorrelation of morphological criteria with the rate of growth in carcinoma of the breast
Original languageGerman
Pages (from-to)24-29
Number of pages6
JournalUnknown Journal
Volume43
Issue numberSpec. Iss. 1
DOIs
StatePublished - 1983
Externally publishedYes

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