Klinische Bedeutung von p53 Tumor-Suppressor-Gen Mutationen beim Adenocarcinom im Barrett-Osophagus.

Translated title of the contribution: Clinical significance of p53 tumor suppressor gene mutations in adenocarcinoma in Barrett esophagus

P. M. Schneider, A. H. Hölscher, S. Wegerer, U. König, K. Becker, J. R. Siewert

Research output: Contribution to journalArticlepeer-review

Abstract

p53 mutations are involved in the pathogenesis of adenocarcinomas in Barrett's esophagus. Our study included patients with histopathologically classified Barrett's cancer and shows that p53 mutations are clinically important for curatively resected (R0) Barrett's cancer. It appears that the p53 mutation status is a promising parameter for the definition of risk groups after potentially curative resections.

Translated title of the contributionClinical significance of p53 tumor suppressor gene mutations in adenocarcinoma in Barrett esophagus
Original languageGerman
Pages (from-to)495-499
Number of pages5
JournalLangenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress
Volume115
Issue numberSuppl I
StatePublished - 1998

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