Kleinzelliges Lungenkarzinom

Translated title of the contribution: Small Cell Lung Cancer

Niels Reinmuth, Hans Hoffmann

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Small cell lung cancer accounts for roughly 14% of all lung cancers and is characterized by rapid progression, early distant metastasis and poor prognosis. Only a minority of patients presents with early stage disease upon initial diagnosis where surgical resection may be discussed. In addition, various treatment modalities demonstrate effectiveness including chemotherapy and radiotherapy. However, although most patients respond to platinum doublet chemotherapy, virtually all patients with metastatic disease eventually develop tumor progression for which there are limited treatment options. Novel therapeutic approaches such as immune checkpoint inhibitors or the antibody drug conjugate rovalpituzumab tesirine show promising results in early clinical trials and might broaden our treatment options in the future.

Translated title of the contributionSmall Cell Lung Cancer
Original languageGerman
Pages (from-to)103-116
Number of pages14
JournalZentralblatt fur Chirurgie - Zeitschrift fur Allgemeine, Viszeral- und Gefasschirurgie
Volume143
Issue number1
DOIs
StatePublished - 1 Feb 2018
Externally publishedYes

Fingerprint

Dive into the research topics of 'Small Cell Lung Cancer'. Together they form a unique fingerprint.

Cite this