Kinetic profiles of diacetoxyscirpenol and two of its metabolites in blood serum of pigs

J. Bauer, W. Bollwahn, M. Gareis, B. Gedek, K. Heinritzi

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Orally administered diacetoxyscirpenol (2 mg/kg of body weight) was rapidly absorbed into the blood serum of pigs; within 1 h, the highest amounts of diacetoxyscirpenol (9.6 to 21.9 ng/ml) were detected. Two metabolites of diacetoxyscirpenol were identified by gas chromatography-mass spectroscopy as monoacetoxyscirpenol and scirpenetriol. The three trichothecenes were present in the blood serum of pigs for only 24 h, indicating a rapid metabolism of these compounds.

Original languageEnglish
Pages (from-to)842-845
Number of pages4
JournalApplied and Environmental Microbiology
Volume49
Issue number4
DOIs
StatePublished - 1985
Externally publishedYes

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