JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility

Minhui Lin; Karin Nebral; Christoph G.W. Gertzen; Ithamar Ganmore; Oskar A. Haas; Sanil Bhatia; Ute Fischer; Michaela Kuhlen; Holger Gohlke; Shai Izraeli; Jan Trka; Jianda Hu; Arndt Borkhardt; Julia Hauer; Franziska Auer

doi:10.1038/s41375-019-0459-z

JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility

Minhui Lin, Karin Nebral, Christoph G.W. Gertzen, Ithamar Ganmore, Oskar A. Haas, Sanil Bhatia, Ute Fischer, Michaela Kuhlen, Holger Gohlke, Shai Izraeli, Jan Trka, Jianda Hu, Arndt Borkhardt, Julia Hauer, Franziska Auer

Research output: Contribution to journal › Letter › peer-review

9 Scopus citations

Original language	English
Pages (from-to)	2331-2335
Number of pages	5
Journal	Leukemia
Volume	33
Issue number	9
DOIs	https://doi.org/10.1038/s41375-019-0459-z
State	Published - 1 Sep 2019
Externally published	Yes

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10.1038/s41375-019-0459-z

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@article{5109e97520df466db27d03bdc1ca2754,

title = "JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility",

author = "Minhui Lin and Karin Nebral and Gertzen, {Christoph G.W.} and Ithamar Ganmore and Haas, {Oskar A.} and Sanil Bhatia and Ute Fischer and Michaela Kuhlen and Holger Gohlke and Shai Izraeli and Jan Trka and Jianda Hu and Arndt Borkhardt and Julia Hauer and Franziska Auer",

note = "Funding Information: We are indebted to all members of our groups for useful discussions and for their critical reading of the manuscript. Special thanks go to Silke Furlan, Friederike Opitz and Bianca Killing. F.A. is supported by the Deutsche For-schungsgemeinschaft (DFG, AU 525/1-1). J.H. has been supported by the German Children{\textquoteright}s Cancer Foundation (Translational Oncology Program 70112951), the German Carreras Foundation (DJCLS 02R/2016), Kinderkrebsstiftung (2016/2017) and ERA PerMed GEPARD. Support by Israel Science Foundation, ERA-NET and Science Ministry (SI). A. B. is supported by the German Consortium of Translational Cancer Research, DKTK. We are grateful to the J{\"u}lich Supercomputing Centre at the Forschungszemtrum J{\"u}lich for granting computing time on the supercomputer JURECA (NIC project ID HKF7) and to the “Zentrum f{\"u}r Informations-und Medientechnologie” (ZIM) at the Heinrich Heine University D{\"u}sseldorf for providing computational support to H. G. The study was performed in the framework of COST action CA16223 “LEGEND”.",

year = "2019",

month = sep,

day = "1",

doi = "10.1038/s41375-019-0459-z",

language = "English",

volume = "33",

pages = "2331--2335",

journal = "Leukemia",

issn = "0887-6924",

publisher = "Nature Publishing Group",

number = "9",

}

TY - JOUR

T1 - JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia

T2 - a synergizing germline susceptibility

AU - Lin, Minhui

AU - Nebral, Karin

AU - Gertzen, Christoph G.W.

AU - Ganmore, Ithamar

AU - Haas, Oskar A.

AU - Bhatia, Sanil

AU - Fischer, Ute

AU - Kuhlen, Michaela

AU - Gohlke, Holger

AU - Izraeli, Shai

AU - Trka, Jan

AU - Hu, Jianda

AU - Borkhardt, Arndt

AU - Hauer, Julia

AU - Auer, Franziska

N1 - Funding Information: We are indebted to all members of our groups for useful discussions and for their critical reading of the manuscript. Special thanks go to Silke Furlan, Friederike Opitz and Bianca Killing. F.A. is supported by the Deutsche For-schungsgemeinschaft (DFG, AU 525/1-1). J.H. has been supported by the German Children’s Cancer Foundation (Translational Oncology Program 70112951), the German Carreras Foundation (DJCLS 02R/2016), Kinderkrebsstiftung (2016/2017) and ERA PerMed GEPARD. Support by Israel Science Foundation, ERA-NET and Science Ministry (SI). A. B. is supported by the German Consortium of Translational Cancer Research, DKTK. We are grateful to the Jülich Supercomputing Centre at the Forschungszemtrum Jülich for granting computing time on the supercomputer JURECA (NIC project ID HKF7) and to the “Zentrum für Informations-und Medientechnologie” (ZIM) at the Heinrich Heine University Düsseldorf for providing computational support to H. G. The study was performed in the framework of COST action CA16223 “LEGEND”.

PY - 2019/9/1

Y1 - 2019/9/1

UR - http://www.scopus.com/inward/record.url?scp=85064231953&partnerID=8YFLogxK

U2 - 10.1038/s41375-019-0459-z

DO - 10.1038/s41375-019-0459-z

M3 - Letter

C2 - 30967616

AN - SCOPUS:85064231953

SN - 0887-6924

VL - 33

SP - 2331

EP - 2335

JO - Leukemia

JF - Leukemia

IS - 9

ER -

JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility

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