Iron-catalyzed reduction of carboxylic esters to alcohols

Kathrin Junge, Bianca Wendt, Shaolin Zhou, Matthias Beller

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

A novel catalytic system formed from Fe(stearate)2/NH 2CH2CH2NH2 and polymethylhydrosiloxane was directly developed for the hydrosilylation of carboxylic acid esters to alcohols. The catalytic method exhibits broad substrate scope, including 20 aliphatic, aromatic, and heterocyclic esters. The corresponding alcohols are obtained in moderate to very good yields. The first iron-catalyzed hydrosilylation of carboxylic acid esters to alcohols is described. A catalytic system formed by Fe(stearate)2/NH 2CH2CH2NH2 and polymethylhydrosiloxane (PMHS) is used for this transformation, which has a broad substrate scope, including 20 aliphatic, aromatic, and heterocyclic esters. The corresponding alcohols are obtained in moderate to very good yields.

Original languageEnglish
Pages (from-to)2061-2065
Number of pages5
JournalEuropean Journal of Organic Chemistry
Issue number11
DOIs
StatePublished - Apr 2013
Externally publishedYes

Keywords

  • Alcohols
  • Esters
  • Homogeneous catalysis
  • Hydrosilanes
  • Iron
  • Reduction
  • Synthetic methods

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