Iron-catalyzed asymmetric epoxidation of aromatic alkenes using hydrogen peroxide

Feyissa Gadissa Gelalcha, Bianca Bitterlich, Gopinathan Anilkumar, Kin Tse Man, Matthias Beller

Research output: Contribution to journalArticlepeer-review

219 Scopus citations

Abstract

(Chemical Equation Presented) Ironing out the wrinkles: Highly enantioselective catalytic asymmetric epoxidation of aromatic alkenes with hydrogen peroxide proceeds smoothly in the presence of a catalyst system consisting of ferric hexahydrate, pyridine-2,6-dicarboxylic acid, and the novel chiral ligand 1 in 2-methylbutane-2-ol solvent at room temperature within 1 h (see scheme; Bn = benzyl).

Original languageEnglish
Pages (from-to)7293-7296
Number of pages4
JournalAngewandte Chemie International Edition in English
Volume46
Issue number38
DOIs
StatePublished - 2007
Externally publishedYes

Keywords

  • Asymmetric catalysis
  • Epoxidation
  • Hydrogen peroxide
  • Iron

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