Abstract
The discipline of Toxicology is concerned with the health risks of human exposure to chemicals or radiation. According to Paracelsu' paradigm, Toxicology is charged with describing the adverse effects of chemicals in a qualitative sense, and with evaluating them quantitatively by determining how much of a chemical is required to produce a given response. Taking these two together, we can describe the intrinsic properties of an agent (hazard identification) and we can estimate the amount of the chemical required to produce these properties (risk characterization).
| Original language | English |
|---|---|
| Title of host publication | Toxicology and Risk Assessment |
| Subtitle of host publication | A Comprehensive Introduction |
| Publisher | John Wiley & Sons, Ltd |
| Pages | 1-18 |
| Number of pages | 18 |
| ISBN (Print) | 9780470868935 |
| DOIs | |
| State | Published - 8 Feb 2008 |
Keywords
- Dose-response relationship
- Enterohepatic circulation
- Gap-junction-mediated intercellular communication
- No-observable-effect level (NOEL)
- Occupational exposure standards
- Oral cavity and gastrointestinal tract
- Persistent accumulated damage
- Phototoxicity and photoallergic reactions
- Single occluded patch
- Tumor-suppressor genes and apoptosis
