Interventioneller Verschluss angeborener Ventrikelseptumdefekte: Breitere Indikationsstellung dank neuer Implantate

Translated title of the contribution: Transcatheter closure of congenital ventricular septal defects

P. Ewert, O. Kretschmar, B. Peters, H. Abdul Khaliq, N. Nagdyman, I. Schulze-Neick, J. Bass, T. P. Lê, P. E. Lange

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


We report on the transcatheter closure of ventricular septal defects (VSD) in 26 patients with Amplatzer Occluders and Nit-Occlud Coil Systems. Twenty-one patients had a perimembranous and 5 patients a muscular VSD. Patients' age range was 5 months to 59 years (median 8 years) and their body weight 4.5 kg to 167 kg (median 28 kg). Defect diameters were 3-11 mm (median 5 mm). Sixteen patients had left ventricular volume overload and 7 patients pulmonary hypertension (median 50% of systemic pressure). Seven patients suffered from trivial or mild aortic regurgitation. Twenty-eight devices (4-12 mm; median 8 mm) were implanted (16 Amplatzer, 12 Nit-Occlud) through sheaths of 4F to 9F (median 7F). Fluoroscopy times were 8.3-56.5 min (median 26.2 min). One coil was surgically explanted directly after intervention. One patient needed pulmonary banding due to additional VSDs. After a follow-up of 7 months (1-12 months), 2 patients had a small and 9 a minimal residual shunt. Thirteen defects were completely closed. Transcatheter closure of VSDs with new devices seems to be a promising therapy for suitable defects in different hemodynamic conditions in patients of every age.

Translated title of the contributionTranscatheter closure of congenital ventricular septal defects
Original languageGerman
Pages (from-to)147-155
Number of pages9
JournalZeitschrift fur Kardiologie
Issue number2
StatePublished - Feb 2004
Externally publishedYes


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