Interaction of biomechanics and metabolic activity in abdominal aortic aneurysm wall

Christian Reeps, M. Gee, J. Pelisek, A. Maier, M. Gurdan, W. Wall, M. Schwaiger, M. Essler, H. H. Eckstein

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

The interplay of biomechanical stresses to subsequent histopathological response in the wall of abdominal aortic aneurysm (AAA) is poorly understood and investigated. Meanwhile individually acting forces can be calculated precisely by wall stress analyses as well as biologic activity of AAA wall can be studied in-vivo by 18F-fluorodeoxyglucose positron emission tomography. For better insights in stresstissue interactions and methodical reasons we studied therefore the correlation of metabolic activity with the results of computational wall stress analyses in two patients. Thereby, areas of highest metabolic activity were well correlated to regions with highest computational peak wall stress for these two patients. To proof these findings further analyses in 25 patients are planned and the results will be presented.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering
Subtitle of host publicationImage Processing, Biosignal Processing, Modelling and Simulation, Biomechanics
PublisherSpringer Verlag
Pages659-661
Number of pages3
Edition4
ISBN (Print)9783642038815
DOIs
StatePublished - 2009
EventWorld Congress on Medical Physics and Biomedical Engineering: Image Processing, Biosignal Processing, Modelling and Simulation, Biomechanics - Munich, Germany
Duration: 7 Sep 200912 Sep 2009

Publication series

NameIFMBE Proceedings
Number4
Volume25
ISSN (Print)1680-0737

Conference

ConferenceWorld Congress on Medical Physics and Biomedical Engineering: Image Processing, Biosignal Processing, Modelling and Simulation, Biomechanics
Country/TerritoryGermany
CityMunich
Period7/09/0912/09/09

Keywords

  • Abdominal aortic aneurysm
  • Finite element analysis
  • Glucose metabolism
  • Stress tissue interaction

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