Initial Raymond–Roy Occlusion Classification but not Packing Density Defines Risk for Recurrence after Aneurysm Coiling

Tobias Greve, Maximilian Sukopp, Maria Wostrack, Egon Burian, Claus Zimmer, Benjamin Friedrich

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Purpose: After coil embolization of intracranial aneurysms, it is currently not well understood whether the initial coil packing density or the type of aneurysm residual perfusion, depicted by the modified Raymond-Roy occlusion classification, primarily effects the rate of aneurysm recurrence. We hypothesized that these factors interact and only one remains an independent risk factor. Methods: In this single center retrospective study, 440 patients with intracranial ruptured and unruptured aneurysms between 2010 and 2017 were screened. A total of 267 patients treated with stand-alone coiling, with or without stent or balloon assistance were included (age 54.1 ± 12.2 years, sex 70.4% female). Flow diverter or Woven EndoBridge (WEB) device implantation were exclusion criteria. Results: Using a binary logistic regression model, independent risk factors for aneurysm recurrence were postinterventional modified Raymond-Roy occlusion classification class (Odds ratio [OR] 1.747, 95% confidence interval [CI] 1.231–2.480) and aneurysm diameter (OR 1.145, CI 1.032–1.271). A trend towards a higher recurrence in ruptured aneurysms did not reach significance (OR 1.656, CI 0.863–3.179). Aneurysm localization, packing density, and neck width were not independently associated with aneurysm recurrence. Conclusion: Independent risk factors for aneurysm recurrence after coil embolization with and without stent or balloon assistance were aneurysm diameter and postinterventional grading within the modified Raymond-Roy occlusion classification. Packing density interacted with the latter and was not independently associated to recurrence.

Original languageEnglish
Pages (from-to)391-399
Number of pages9
JournalClinical Neuroradiology
Volume31
Issue number2
DOIs
StatePublished - Jun 2021
Externally publishedYes

Keywords

  • Aneurysm regrowth
  • Balloon-assisted coiling
  • Endovascular treatment
  • Intracranial aneurysm

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