TY - JOUR
T1 - Inhalative Analgosedierung auf der Intensivstation
T2 - Gefahr einer malignen Hyperthermie
AU - Klingler, W.
AU - Pfenninger, E.
N1 - Publisher Copyright:
© 2018, Springer Medizin Verlag GmbH, ein Teil von Springer Nature.
PY - 2020/3/1
Y1 - 2020/3/1
N2 - Background: According to the 2010 S3 Guidelines, analgosedation is an option for ventilated patients in intensive care units (ICU). Therefore, adverse effects of volatile anesthetics can occur in areas outside of surgical medical fields. Objective: The aim is to inform ICU physicians about the clinical and legal challenges of a life-threatening pharmacogenetic reaction to inhalational anesthetics, malignant hyperthermia (MH). Discussion: Consequences of an MH crisis for doctors, patients, and relatives regarding patient rights legislation, as well as insurance and employment issues with respect to the German Genetic Diagnostics Act are discussed.
AB - Background: According to the 2010 S3 Guidelines, analgosedation is an option for ventilated patients in intensive care units (ICU). Therefore, adverse effects of volatile anesthetics can occur in areas outside of surgical medical fields. Objective: The aim is to inform ICU physicians about the clinical and legal challenges of a life-threatening pharmacogenetic reaction to inhalational anesthetics, malignant hyperthermia (MH). Discussion: Consequences of an MH crisis for doctors, patients, and relatives regarding patient rights legislation, as well as insurance and employment issues with respect to the German Genetic Diagnostics Act are discussed.
KW - Dantrolene
KW - General anesthesia
KW - German Genetic Diagnostics Act
KW - Malignant hyperthermia
KW - Pharmacogenetics
UR - http://www.scopus.com/inward/record.url?scp=85052513002&partnerID=8YFLogxK
U2 - 10.1007/s00063-018-0453-7
DO - 10.1007/s00063-018-0453-7
M3 - Artikel
C2 - 30076433
AN - SCOPUS:85052513002
SN - 2193-6218
VL - 115
SP - 101
EP - 106
JO - Medizinische Klinik - Intensivmedizin und Notfallmedizin
JF - Medizinische Klinik - Intensivmedizin und Notfallmedizin
IS - 2
ER -