Infrared contact coagulation: A new approach for local hyperthermic therapy of solid animal tumors

C. Lersch, C. Hammer, O. Ganghoff, J. Meyer, W. Brendel, F. Krombach, G. Nath

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Infrared contact coagulation (ICC) was evaluated in 3 different tumor models. 56-94% of all tumor-bearing rats, hamsters or mice were cured by ICC, whereas 100% of the controls died. The possibility that long-lasting immunological resistance might develop against the tumor after ICC was investigated by repeated tumor challenge. Cytotoxicity against tumor cells of host thymocytes and splenocytes following ICC was demonstrated in a Winn assay. The production of a mainly T-cell-dependent immune response could be due to ICC-induced antigenic changes in the tumor cells.

Original languageEnglish
Pages (from-to)442-445
Number of pages4
JournalOncology
Volume41
Issue number6
DOIs
StatePublished - 1984
Externally publishedYes

Fingerprint

Dive into the research topics of 'Infrared contact coagulation: A new approach for local hyperthermic therapy of solid animal tumors'. Together they form a unique fingerprint.

Cite this