Influence of diesel soot particles and sulfite on functions of polymorphonuclear leukocytes

S. C. Hippeli; E. F. Elstner

doi:10.3109/10715769009109665

Influence of diesel soot particles and sulfite on functions of polymorphonuclear leukocytes

S. C. Hippeli, E. F. Elstner

Life Sciences

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Aqueous suspensions of diesel soot particles in combination with sulfite influence certain functions of human polymorphonuclear neutrophils in vitro. Chemiluminescence, generated after activation by opsonized zymosan as well as oxygen uptake were decreased, whereas phagocytosis was increased. An enhancement of degranulation could not be observed. The single substances show little or no effects on the above properties. The results indicate that combinations of air pollutants such as diesel soot and sulfite may modulate vital functions of activated leukocytes in vivo.

Original language	English
Pages (from-to)	29-38
Number of pages	10
Journal	Free Radical Research
Volume	11
Issue number	1-3
DOIs	https://doi.org/10.3109/10715769009109665
State	Published - 1990

Keywords

Diesel particles
Oxygen activation
Phagocytosis
Polymorphonuclear leukocytes
Sulfite

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title = "Influence of diesel soot particles and sulfite on functions of polymorphonuclear leukocytes",

abstract = "Aqueous suspensions of diesel soot particles in combination with sulfite influence certain functions of human polymorphonuclear neutrophils in vitro. Chemiluminescence, generated after activation by opsonized zymosan as well as oxygen uptake were decreased, whereas phagocytosis was increased. An enhancement of degranulation could not be observed. The single substances show little or no effects on the above properties. The results indicate that combinations of air pollutants such as diesel soot and sulfite may modulate vital functions of activated leukocytes in vivo.",

keywords = "Diesel particles, Oxygen activation, Phagocytosis, Polymorphonuclear leukocytes, Sulfite",

author = "Hippeli, {S. C.} and Elstner, {E. F.}",

note = "Funding Information: This work was supported by “Bayerisches Staatsministrium {\textquoteleft}fur Landesentwicklung und Umweltschutz”, Miinchen, FRG.",

year = "1990",

doi = "10.3109/10715769009109665",

language = "English",

volume = "11",

pages = "29--38",

journal = "Free Radical Research",

issn = "1071-5762",

publisher = "Informa Healthcare",

number = "1-3",

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TY - JOUR

T1 - Influence of diesel soot particles and sulfite on functions of polymorphonuclear leukocytes

AU - Hippeli, S. C.

AU - Elstner, E. F.

N1 - Funding Information: This work was supported by “Bayerisches Staatsministrium ‘fur Landesentwicklung und Umweltschutz”, Miinchen, FRG.

PY - 1990

Y1 - 1990

N2 - Aqueous suspensions of diesel soot particles in combination with sulfite influence certain functions of human polymorphonuclear neutrophils in vitro. Chemiluminescence, generated after activation by opsonized zymosan as well as oxygen uptake were decreased, whereas phagocytosis was increased. An enhancement of degranulation could not be observed. The single substances show little or no effects on the above properties. The results indicate that combinations of air pollutants such as diesel soot and sulfite may modulate vital functions of activated leukocytes in vivo.

AB - Aqueous suspensions of diesel soot particles in combination with sulfite influence certain functions of human polymorphonuclear neutrophils in vitro. Chemiluminescence, generated after activation by opsonized zymosan as well as oxygen uptake were decreased, whereas phagocytosis was increased. An enhancement of degranulation could not be observed. The single substances show little or no effects on the above properties. The results indicate that combinations of air pollutants such as diesel soot and sulfite may modulate vital functions of activated leukocytes in vivo.

KW - Diesel particles

KW - Oxygen activation

KW - Phagocytosis

KW - Polymorphonuclear leukocytes

KW - Sulfite

UR - http://www.scopus.com/inward/record.url?scp=0025616117&partnerID=8YFLogxK

U2 - 10.3109/10715769009109665

DO - 10.3109/10715769009109665

M3 - Article

C2 - 2074047

AN - SCOPUS:0025616117

SN - 1071-5762

VL - 11

SP - 29

EP - 38

JO - Free Radical Research

JF - Free Radical Research

IS - 1-3

ER -

Influence of diesel soot particles and sulfite on functions of polymorphonuclear leukocytes

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Keywords

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