Individualized radiotherapy by combining high-end irradiation and magnetic resonance imaging

Stephanie E. Combs; Fridtjof Nüsslin; Jan J. Wilkens

doi:10.1007/s00066-016-0944-5

Individualized radiotherapy by combining high-end irradiation and magnetic resonance imaging

Translated title of the contribution: Individualized radiotherapy by combining high-end irradiation and magnetic resonance imaging

Stephanie E. Combs, Fridtjof Nüsslin, Jan J. Wilkens

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Image-guided radiotherapy (IGRT) has been integrated into daily clinical routine and can today be considered the standard especially with high-dose radiotherapy. Currently imaging is based on MV- or kV-CT, which has clear limitations especially in soft-tissue contrast. Thus, combination of magnetic resonance (MR) imaging and high-end radiotherapy opens a new horizon. The intricate technical properties of MR imagers pose a challenge to technology when combined with radiation technology. Several solutions that are almost ready for routine clinical application have been developed. The clinical questions include dose-escalation strategies, monitoring of changes during treatment as well as imaging without additional radiation exposure during treatment.

Translated title of the contribution	Individualized radiotherapy by combining high-end irradiation and magnetic resonance imaging
Original language	English
Pages (from-to)	209-215
Number of pages	7
Journal	Strahlentherapie und Onkologie
Volume	192
Issue number	4
DOIs	https://doi.org/10.1007/s00066-016-0944-5
State	Published - 1 Apr 2016
Externally published	Yes

Keywords

Image-guided radiotherapy
Individualized medicine
Magnetic resonance-guided radiotherapy
Organ sparing treatments
Organs at risk

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10.1007/s00066-016-0944-5

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abstract = "Image-guided radiotherapy (IGRT) has been integrated into daily clinical routine and can today be considered the standard especially with high-dose radiotherapy. Currently imaging is based on MV- or kV-CT, which has clear limitations especially in soft-tissue contrast. Thus, combination of magnetic resonance (MR) imaging and high-end radiotherapy opens a new horizon. The intricate technical properties of MR imagers pose a challenge to technology when combined with radiation technology. Several solutions that are almost ready for routine clinical application have been developed. The clinical questions include dose-escalation strategies, monitoring of changes during treatment as well as imaging without additional radiation exposure during treatment.",

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AU - Nüsslin, Fridtjof

AU - Wilkens, Jan J.

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Individualized radiotherapy by combining high-end irradiation and magnetic resonance imaging

Abstract

Keywords

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