Indications for Use of Drug-Coated Balloons in Coronary Intervention: Academic Research Consortium Position Statement

  • Simone Fezzi
  • , Patrick W. Serruys
  • , Bernardo Cortese
  • , Bruno Scheller
  • , Fernando Alfonso
  • , Raban Jeger
  • , Antonio Colombo
  • , Michael Joner
  • , Eun Seok Shin
  • , Franz Kleber
  • , Azeem Latib
  • , Tuomas T. Rissanen
  • , Simon Eccleshall
  • , Flavio Ribichini
  • , Ling Tao
  • , Bon Kwon Koo
  • , Alaide Chieffo
  • , Junbo Ge
  • , Juan F. Granada
  • , Hans Peter Stoll
  • Christian Spaulding, Rafael Cavalcante, Alexandre Abizaid, Takashi Muramatsu, Konstantinos Dean Boudoulas, Ron Waksman, Roxana Mehran, Donald Cutlip, Mitchell Krucoff, Gregg W. Stone, Scot Garg, Yoshinobu Onuma

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

The Drug-Coated Balloon (DCB) Academic Research Consortium project originated from the need to overcome the lack of standardization and comparability among studies focusing on drug-coated balloon treatment. The DCB Academic Research Consortium represents a collaborative effort between academic research organizations and the most renowned interventional cardiology societies focusing on percutaneous coronary intervention in Europe, the United States, and Asia. The present consensus document provides a classification of DCB technologies, antiproliferative drugs, and types of elution and coatings. Moreover, by reviewing the available evidence on the use of DCBs for several lesion (restenosis, de novo small and large vessels, bifurcations) and clinical (acute coronary syndromes, diabetes mellitus, multivessel disease, high bleeding risk) settings, it seeks to provide reasonable suggestions for their clinical use. Last, this paper outlines the processes involved in optimal “lesion preparation” before the use of DCBs and the criteria used for assessing results following their use.

Original languageEnglish
Pages (from-to)1170-1202
Number of pages33
JournalJournal of the American College of Cardiology
Volume86
Issue number15
DOIs
StatePublished - 14 Oct 2025

Keywords

  • coronary artery disease
  • drug-coated balloon
  • percutaneous coronary intervention

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