INCIDENCE AND SEVERITY OF ANAPHYLACTOID REACTIONS TO COLLOID VOLUME SUBSTITUTES

J. Ring, K. Messmer

Research output: Contribution to journalArticlepeer-review

1025 Scopus citations

Abstract

All available colloid volume substitutes carry the risk of anaphylactoid reactions. In a multicentre prospective trial, 69 cases of anaphylactoid reactions have been observed among 200 906 infusions of colloid volume substitutes. The frequency of severe reactions (shock, cardiac and/or respiratory arrest) was 0.003% for plasma-protein solutions, 0.006% for hydroxyethyl starch, 0.008% for dextran, and 0.038% for gelatin solutions.

Original languageEnglish
Pages (from-to)466-469
Number of pages4
JournalThe Lancet
Volume309
Issue number8009
DOIs
StatePublished - 26 Feb 1977
Externally publishedYes

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