Incidence and predictors of stent thrombosis after endovascular revascularisation of the superficial femoral artery

Christian Bradaric, Tobias Koppara, Arne Müller, Bernhard Haller, Ilka Ott, Salvatore Cassese, Massimiliano Fusaro, Adnan Kastrati, Karl Ludwig Laugwitz, Tareq Ibrahim

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Aims: The aims of this study were to assess the incidence and predictors of superficial femoral artery (SFA) stent thrombosis (ST) in a large patient cohort. Methods and results: A total of 984 stented SFA lesions were retrospectively analysed in 717 patients. We observed an overall ST rate of 7.5% (74/984): 14% occurred early within 30 days after stenting, 51% during the first year thereafter and 35% later than one year. The estimated five-year probability of ST was 13.4% (95% confidence interval [CI]: 10.0% to 16.7%). Significant predictors of ST were stent length (hazard ratio [HR] 1.09, 95% CI: 1.06 to 1.11, p<0.001), lesion length (HR 1.10, 95% CI: 1.08 to 1.13, p<0.001), female gender (HR 1.79, 95% CI: 1.12 to 2.86, p=0.015), chronic total occlusion (CTO) (HR 4.21, 95% CI: 2.51 to 7.05, p<0.001), implantation of more than one stent (two stents: HR 6.06, 95% CI: 3.35 to 11.0, p<0.001; three or more stents: HR 16.83, 95% CI: 9.43 to 30.0, p<0.001) as well as lesion complexity criteria as expressed by TASC II C/D (HR 17.7, 95% CI: 5.56 to 56.1, p<0.001). Conclusions: ST after SFA stenting was a common adverse event in our cohort and peaked during the first year after stent implantation. Independent predictors of ST included lesion length and stent length, female gender, presence of CTO, number of implanted stents and lesion complexity.

Original languageEnglish
Pages (from-to)E1107-E1114
JournalEuroIntervention
Volume15
Issue number12
DOIs
StatePublished - Dec 2019

Keywords

  • Critical limb ischaemia
  • Femoropopliteal disease
  • Stent thrombosis

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