TY - GEN
T1 - In vivo time-resolved optical spectroscopy of mice
AU - Graves, E. E.
AU - Petrovsky, A.
AU - Weissleder, R.
AU - Ntziachristos, V.
N1 - Publisher Copyright:
© 2002 Optical Society of America.
PY - 2002
Y1 - 2002
N2 - A time-correlated single photon counting (TCSPC) system has been developed for use with living specimens as part of a fluorescence-mediated molecular tomography scanner. This system has been used to measure the bulk optical properties of mouse tissues. Absorption coefficients were found to be 0.15 – 0.3 cm-1, while reduced scattering coefficients were measured to be 1.5 – 5.0 cm-1. The variability of the results recommend the determination of optical properties for each subject in order to improve the accuracy of fluorescence tomography reconstruction.
AB - A time-correlated single photon counting (TCSPC) system has been developed for use with living specimens as part of a fluorescence-mediated molecular tomography scanner. This system has been used to measure the bulk optical properties of mouse tissues. Absorption coefficients were found to be 0.15 – 0.3 cm-1, while reduced scattering coefficients were measured to be 1.5 – 5.0 cm-1. The variability of the results recommend the determination of optical properties for each subject in order to improve the accuracy of fluorescence tomography reconstruction.
UR - http://www.scopus.com/inward/record.url?scp=85135900602&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85135900602
T3 - Optics InfoBase Conference Papers
SP - 371
EP - 373
BT - Biomedical Topical Meeting, BIOMED 2002
PB - Optica Publishing Group (formerly OSA)
T2 - Biomedical Topical Meeting, BIOMED 2002
Y2 - 7 April 2002 through 10 April 2002
ER -