In vivo time-resolved optical spectroscopy of mice

E. E. Graves, A. Petrovsky, R. Weissleder, V. Ntziachristos

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


A time-correlated single photon counting (TCSPC) system has been developed for use with living specimens as part of a fluorescence-mediated molecular tomography scanner. This system has been used to measure the bulk optical properties of mouse tissues. Absorption coefficients were found to be 0.15 – 0.3 cm-1, while reduced scattering coefficients were measured to be 1.5 – 5.0 cm-1. The variability of the results recommend the determination of optical properties for each subject in order to improve the accuracy of fluorescence tomography reconstruction.

Original languageEnglish
Title of host publicationBiomedical Topical Meeting, BIOMED 2002
PublisherOptica Publishing Group (formerly OSA)
Number of pages3
ISBN (Electronic)1557527024
StatePublished - 2002
Externally publishedYes
EventBiomedical Topical Meeting, BIOMED 2002 - Miami Beach, United States
Duration: 7 Apr 200210 Apr 2002

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701


ConferenceBiomedical Topical Meeting, BIOMED 2002
Country/TerritoryUnited States
CityMiami Beach


Dive into the research topics of 'In vivo time-resolved optical spectroscopy of mice'. Together they form a unique fingerprint.

Cite this