In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector

P. Laurette; C. Cao; D. Ramanujam; M. Schwaderer; T. Lueneburg; S. Kuss; L. Weiss; R. Dilshat; E. E.M. Furlong; F. Rezende; S. Engelhardt; R. Gilsbach

doi:10.1161/CIRCRESAHA.123.323854

In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector

P. Laurette, C. Cao, D. Ramanujam, M. Schwaderer, T. Lueneburg, S. Kuss, L. Weiss, R. Dilshat, E. E.M. Furlong, F. Rezende, S. Engelhardt, R. Gilsbach

Chair of Pharmacology and Toxicology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Original language	English
Pages (from-to)	223-225
Number of pages	3
Journal	Circulation Research
Volume	134
Issue number	2
DOIs	https://doi.org/10.1161/CIRCRESAHA.123.323854
State	Published - 19 Jan 2024

Keywords

epigenetic repression
gene editing
gene silencing
genetic therapy
genomics

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10.1161/CIRCRESAHA.123.323854

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title = "In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector",

keywords = "epigenetic repression, gene editing, gene silencing, genetic therapy, genomics",

author = "P. Laurette and C. Cao and D. Ramanujam and M. Schwaderer and T. Lueneburg and S. Kuss and L. Weiss and R. Dilshat and Furlong, \{E. E.M.\} and F. Rezende and S. Engelhardt and R. Gilsbach",

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doi = "10.1161/CIRCRESAHA.123.323854",

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T1 - In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector

AU - Laurette, P.

AU - Cao, C.

AU - Ramanujam, D.

AU - Schwaderer, M.

AU - Lueneburg, T.

AU - Kuss, S.

AU - Weiss, L.

AU - Dilshat, R.

AU - Furlong, E. E.M.

AU - Rezende, F.

AU - Engelhardt, S.

AU - Gilsbach, R.

PY - 2024/1/19

Y1 - 2024/1/19

KW - epigenetic repression

KW - gene editing

KW - gene silencing

KW - genetic therapy

KW - genomics

UR - http://www.scopus.com/inward/record.url?scp=85182788193&partnerID=8YFLogxK

U2 - 10.1161/CIRCRESAHA.123.323854

DO - 10.1161/CIRCRESAHA.123.323854

M3 - Article

C2 - 38131200

AN - SCOPUS:85182788193

SN - 0009-7330

VL - 134

SP - 223

EP - 225

JO - Circulation Research

JF - Circulation Research

IS - 2

ER -

In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector

Keywords

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