@inbook{b98605bb0df644db898e516e154b2d9f,
title = "In vivo imaging of mitochondria in intact zebrafish larvae",
abstract = "Visualizing neuronal mitochondria in a living, intact mammalian organism is a challenge that can be overcome in zebrafish larvae, which are highly accessible for optical imaging and genetic manipulation. Here, we detail an approach to visualize neuronal mitochondria in sensory Rohon-Beard axons, which allows quantitatively measuring mitochondrial shape, dynamics, and transport in vivo. This provides a useful assay for basic studies exploring the behavior of neuronal mitochondria in their natural habitat, for revealing the influence that disease-related alterations have on this behavior and for testing pharmacological compounds and genetic manipulations that might ameliorate disease-related mitochondrial phenotypes in neurons.",
keywords = "Axonal transport, In vivo imaging, Microscopy, Zebrafish",
author = "Dominik Paquet and Gabriela Pluci{\'n}ska and Thomas Misgeld",
note = "Publisher Copyright: {\textcopyright} 2014 Elsevier Inc. B.V. All rights reserved.",
year = "2014",
doi = "10.1016/B978-0-12-801415-8.00009-6",
language = "English",
series = "Methods in Enzymology",
publisher = "Academic Press Inc.",
number = "C",
pages = "151--164",
booktitle = "Methods in Enzymology",
edition = "C",
}