In-vivo cell and tissue monitoring with active implants

Johannes F. Clauss; Walter Wirths; Michael Roos; Budi Wohrle; Martin Brischwein; Bernhard Wolf

doi:10.1109/EMBC.2015.7320025

In-vivo cell and tissue monitoring with active implants

Johannes F. Clauss
, Walter Wirths
, Michael Roos
, Budi Wohrle
, Martin Brischwein
, Bernhard Wolf

Technical University of Munich

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.

Original language	English
Title of host publication	2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	7087-7090
Number of pages	4
ISBN (Electronic)	9781424492718
DOIs	https://doi.org/10.1109/EMBC.2015.7320025
State	Published - 4 Nov 2015
Event	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy Duration: 25 Aug 2015 → 29 Aug 2015

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume	2015-November
ISSN (Print)	1557-170X

Conference

Conference	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Country/Territory	Italy
City	Milan
Period	25/08/15 → 29/08/15

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1109/EMBC.2015.7320025

Cite this

Clauss, J. F., Wirths, W., Roos, M., Wohrle, B., Brischwein, M., & Wolf, B. (2015). In-vivo cell and tissue monitoring with active implants. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 (pp. 7087-7090). Article 7320025 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2015-November). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7320025

Clauss, Johannes F. ; Wirths, Walter ; Roos, Michael et al. / In-vivo cell and tissue monitoring with active implants. 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 7087-7090 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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title = "In-vivo cell and tissue monitoring with active implants",

abstract = "Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.",

author = "Clauss, \{Johannes F.\} and Walter Wirths and Michael Roos and Budi Wohrle and Martin Brischwein and Bernhard Wolf",

note = "Publisher Copyright: {\textcopyright} 2015 IEEE.; 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 ; Conference date: 25-08-2015 Through 29-08-2015",

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doi = "10.1109/EMBC.2015.7320025",

language = "English",

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Clauss, JF, Wirths, W, Roos, M, Wohrle, B, Brischwein, M & Wolf, B 2015, In-vivo cell and tissue monitoring with active implants. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015., 7320025, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2015-November, Institute of Electrical and Electronics Engineers Inc., pp. 7087-7090, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 25/08/15. https://doi.org/10.1109/EMBC.2015.7320025

In-vivo cell and tissue monitoring with active implants. / Clauss, Johannes F.; Wirths, Walter; Roos, Michael et al.
2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. 7087-7090 7320025 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2015-November).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - In-vivo cell and tissue monitoring with active implants

AU - Clauss, Johannes F.

AU - Wirths, Walter

AU - Roos, Michael

AU - Wohrle, Budi

AU - Brischwein, Martin

AU - Wolf, Bernhard

PY - 2015/11/4

Y1 - 2015/11/4

N2 - Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.

AB - Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.

UR - https://www.scopus.com/pages/publications/84953231281

U2 - 10.1109/EMBC.2015.7320025

DO - 10.1109/EMBC.2015.7320025

M3 - Conference contribution

C2 - 26737925

AN - SCOPUS:84953231281

T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

SP - 7087

EP - 7090

BT - 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015

Y2 - 25 August 2015 through 29 August 2015

ER -

Clauss JF, Wirths W, Roos M, Wohrle B, Brischwein M , Wolf B. In-vivo cell and tissue monitoring with active implants. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. 7087-7090. 7320025. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2015.7320025

In-vivo cell and tissue monitoring with active implants

Abstract

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UN SDGs

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