TY - GEN
T1 - In-vivo cell and tissue monitoring with active implants
AU - Clauss, Johannes F.
AU - Wirths, Walter
AU - Roos, Michael
AU - Wohrle, Budi
AU - Brischwein, Martin
AU - Wolf, Bernhard
N1 - Publisher Copyright:
© 2015 IEEE.
PY - 2015/11/4
Y1 - 2015/11/4
N2 - Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.
AB - Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.
UR - http://www.scopus.com/inward/record.url?scp=84953231281&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2015.7320025
DO - 10.1109/EMBC.2015.7320025
M3 - Conference contribution
C2 - 26737925
AN - SCOPUS:84953231281
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 7087
EP - 7090
BT - 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Y2 - 25 August 2015 through 29 August 2015
ER -
