In Silico Study of the Surface Plasmon Resonance Use for Detecting Cancer in the Colorectal Mucosa

Arthur A. Melo, Eloise P. Rodrigues, Antonio M.N. Lima, Cleumar S. Moreira, Rossana M.S. Cruz

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

This paper presents an in silico study regarding the use of a trapezoidal prism-based surface plasmon resonance sensor to detect cancer in the colorectal mucosa. The parameters of the surface plasmon resonance curves o the multilayered structure operating in the wavelength interrogation mode were studied by exploring the metallic film characteristics. The height of the thin films of gold, silver, and copper was studied to find the best sensitivity. Whereas a p-polarized light beam, with a range of 450 to 820 nm, falls on the multilayered structure at an angle of 68 degrees, the Fresnel equations were chosen to calculate the reflectance curve. From the evaluated results, we realized that the greater results were reached when we used a 40 nm silver film, resulting in 6,454.12 nm/RIU for a sensitivity value.

Original languageEnglish
Title of host publicationI2MTC 2022 - IEEE International Instrumentation and Measurement Technology Conference
Subtitle of host publicationInstrumentation and Measurement under Pandemic Constraints, Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781665483605
DOIs
StatePublished - 2022
Externally publishedYes
Event2022 IEEE International Instrumentation and Measurement Technology Conference, I2MTC 2022 - Ottawa, Canada
Duration: 16 May 202219 May 2022

Publication series

NameConference Record - IEEE Instrumentation and Measurement Technology Conference
ISSN (Print)1091-5281

Conference

Conference2022 IEEE International Instrumentation and Measurement Technology Conference, I2MTC 2022
Country/TerritoryCanada
CityOttawa
Period16/05/2219/05/22

Keywords

  • SPR sensor
  • colorectal cancer
  • thin metal film
  • trapezoidal prism

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